| Brewery | Location |
|---|---|
| Spike Brewery | Gothenburh |
| Spiked Seltzer | |
| Spilker Ales | Cortland, Nebraska |
| Spindle Tap | Houston |
| Spindletap Brewery | Houston |
| Spinnakers Brewpub | Victoria |
| Spitalbrauerei | Regensburg |
| Spiteful Brewing Company | |
| Spoetzl Brewery | Shiner, Texas |
| Spoonwood Brewing Company | Pittsburgh |
| Sports City Cafe & Brewery | La Jolla, California |
| Sprecher Brewing | Glendale, Wisconsin |
| Spring House Brewing Company | Conestoga, Pennsylvania |
| Springdale | Framingham |
| Springfield Brewing | Springfield, Missouri |