| Brewery | Location |
|---|---|
| Southampton Publick House | Southampton, New York |
| Southbound Brewing Company | Savannah |
| Southend Brewery and Smokehouse - Charleston | Charleston, South Carolina |
| Southern Barrell Brewing | Bluffton |
| Southern Brewing Company | Athens, Georgia |
| Southern Grist Brewing Co | |
| Southern Oregon Brewing | Medford |
| Southern Origin Meadery | Canon |
| Southern Pines Brewing Co. | Southern Pines |
| Southern Prohibition Brewery | Hattisburg |
| Southern Range Brewing | |
| Southern Star Brewing Company | Conroe, Texas |
| Southern Tier Brewing Co | Lakewood, New York |
| SouthNorte Beer Company | San Diego |
| Sovereign Brewing | Seattle, Washington |