| Synthesis | Oxbow Brewing Company | Saison | 8.0% |
| Synthesis Analogous | Jester King Craft Brewery | Wild Ale | 5.6% |
| Synthesis Vanilla Chai | Brewlihan Mead Company | | |
| Syracuse Pale Ale | Middle Ages Brewing | American Pale Ale | 5.0% |
| Syrah | Fair Isle Brewing | Fruit and Field Beer | 8.9% |
| Syrah Smile | The Bruery | | |
| Syrah Tilquin à l'Ancienne | Gueuzerie Tilquin | Fruit Lambic | 8.0% |
| Syrah Tilquin à l'Ancienne (2021-2022) | Gueuzerie Tilquin | | 8.0% |
| Syrligt | Dugges Ale/Stillwater Artisinal | Fruit and Field Beer | 4.5% |
| System Of A Stout | Beachwood BBQ & Brewing | Russian Imperial Stout | 11.3% |
| System of a stout | Beachwood Blendery | | |
| System of a Stout - Vanilla | Beachwood BBQ & Brewing | | |
| Systema Naturae 1st Edition Devilwood and Apricot | D9 Brewing | Wild Ale | 6.3% |
| Systema Naturae 8th Edition Jaboticaba and Honeysuckle | D9 Brewing | Wild Ale | 6.0% |
| Systema Natvræ - Lingonberry & Edelweiss | D9 Brewing | Wild Ale | 6.0% |