| Symbiotic Method | City Built Brewing Company | American Imperial Stout | 12.7% |
| Symbol of Renaissance 2021 | Mikkeller Baghaven | | 8.2% |
| Symbology | Burley Oak Brewery | American IPA | 7.2% |
| Symmetric Orchestra | Modern Times | Wild Ale | 7.0% |
| Symmetric Orchestra with Blueberry & Black Currant | Modern Times | | 7.3% |
| Symmetric Orchestra with Guava, Blood Orange, & Hibiscus | Modern Times | Wild Ale | 6.6% |
| Symmetric Orchestra with Passion Fruit & Mango | Modern Times | Wild Ale | 7.4% |
| Symmetrical Garden | Hudson Valley Brewery | | |
| Symmetry | Side prjoect/ Crooked Stave | | 15.0% |
| Symmetry | White Rooster | Flanders Oud Bruin | 7.0% |
| Symohonie Le Grand Assemblage | Ammonite | | |
| Sympathy Weight | Monday Night Brewing | Scotch Ale / Wee Heavy | 12.0% |
| Sympathy Weight - Apple Brandy Barrel Aged | Monday Night Brewing | Scotch Ale / Wee Heavy | 12.0% |
| Sympatric | Speciation Artisan Ales | | |
| Symphonic | Wiseacre | Wild Ale | |