| Slightly Mighty | Dogfish Head Craft Brewery | American IPA | |
| Sligo Red | O'Gara's Bar & Grill | | |
| Slim Digs West Coast IPA | Gold Dot Beer | American IPA | 7.4% |
| Slings & Arrows | Indie Ale House Brewing Company | Berliner Weisse | 4.2% |
| SlingShot | Backpocket Brewing | Dunkelweizen | |
| Slipknot IPA | Full Sail Brewing | English IPA | 7.0% |
| Slippery Detour (Vanilla) | Detour Brewing | Cream Ale | 5.1% |
| Slippery Slope | Brouwerij De Moersleutel | Oatmeal Stout | 12.0% |
| Slippin' Into Darkness | Franklin's Restaurant, Brewery & General Store | Wild Ale | 9.0% |
| Slippy Yips | Aslin Beer Company | | |
| Slipstream Double IPA | Salt Flats Brewing | Imperial IPA | 9.0% |
| Slo Flo | Seven Stills Brewery and Distillery | German Pilsner | 5.1% |
| Slo Turbo | Hoof Hearted Brewing | Imperial IPA | 8.5% |
| SLOambic | Firestone Walker Brewing Co. | Wild Ale | 5.7% |
| Sloe Daze | The Rare Barrel | | |