| Sonorous | Pipeworks Brewing Company | English IPA | 9.0% |
| Sons Of Anarchy Amber Ale | Sudwerk Brewing | American Amber / Red Ale | 4.7% |
| Sons of Darkness | American Solera | American Stout | |
| Sons of Hector | Breton Brewing Co. | English Brown Ale | 5.0% |
| Soon May The Wellerman Come | Bambrass | Russian Imperial Stout | 12.0% |
| Sooper | Sour Cellars | Wild Ale | 5.6% |
| Soothsayer | Brewery Ommegang | Belgian Dark Strong Ale | 8.9% |
| Soothsayer | Lua Brewing | New England IPA | 8.7% |
| Sophia Lambic | Brasserie Cantillon | Lambic | 6.5% |
| Sophie's Sparkling Ale | Appalachian Brewing Company | | 4.3% |
| Sophistry 06 | Lupulin Brewing | American IPA | 7.5% |
| Sophistry 5 | Lupulin Brewing | New England IPA | 7.5% |
| Sophocles | Mystery Brewing Company | | |
| Sophomore Blend | Brewlihan Mead Company | | |
| Sophomoric Saison | 18th Street Brewery | Saison | 7.2% |