| Spiral Staircase | 10 Barrel Brewing Co. | Imperial Porter | 9.7% |
| Spirals | Definitive Brewing Company | Imperial IPA | 8.2% |
| Spirit Animal | Blue Owl Brewing | | |
| Spirit Animal Opal Plum | Jester King / Cloudwater | | 4.5% |
| Spirit Beast | Jackie O's Pub & Brewery | American Strong Ale | 11.0% |
| Spirit Foul | Fair State Brewing Co-op | American IPA | |
| Spirit Mask Cuvee | Calusa Brewing | Wild Ale | |
| Spirit of Danny | Rockyard Brewing | Saison | 8.4% |
| Spirit of Skully #1 Barleywine | Paradox Beer Company | American Barleywine | 15.5% |
| Spirit Talons | Horus Aged Ales | American Imperial Stout | 13.6% |
| Spirits of the Dead | Ex Novo Brewing | American IPA | 7.3% |
| Spiritu Fornicationis | Microbrasserie Goudale | | 9.5% |
| Spiritual Needs | Cigar City Brewing | American Imperial Stout | |
| Spiritual Unrest | Tree House Brewing Company | Sweet / Milk Stout | 8.0% |
| Spiritus Mundi | Incendiary Brewing Company | American Imperial Stout | 13.0% |