| 2190 | Kane Brewing Company | Quadrupel (Quad) | 12.9% |
| 2192 | Kane Brewing Company | American Imperial Stout | 12.4% |
| 21A IPA | 21st Amendment Brewery Cafe | American IPA | 7.2% |
| 21st Amendment / Firestone Walker / Stone El Camino (Un)Real Black Ale | Stone Brewing | American Strong Ale | 9.5% |
| 21st Anniversary | Great Divide Brewing Company | Wild Ale | 6.2% |
| 21st Anniversary | Karl Strauss Brewing Company | Belgian Dark Strong Ale | 10.2% |
| 21st Anniversary | Weyerbacher Brewing Company | American Imperial Stout | 11.9% |
| 21st Anniversary Ale | Hinterland Brewery Restaurant | | 9.4% |
| 21st Anniversary Birthday Suit | Crooked Line Brewing Co | Saison | 6.3% |
| 21st Anniversary Birthday Suit | Uinta Brewing Company | Wild Ale | 6.3% |
| 21st Anniversary Oud Bruin | Sweetwater Brewing - Atlanta | Flanders Oud Bruin | 7.9% |
| 21st Century Means | Stillwater / Cigar City | Saison | 8.5% |
| 22 | Weyerbacher Brewing Company | American Strong Ale | 11.1% |
| 22 Pils | New Glarus Brewing Company | German Pilsner | |
| 2200 4th Birthday Brew | To Øl | English Pale Ale | 5.2% |