| Two Penny Porter | Birrificio Ticinese | American Porter | 8.2% |
| Two Pilots | Sante Adairius Rustic Ales | Saison | 7.0% |
| Two Princes | Streetside Brewery | Fruit and Field Beer | 4.5% |
| Two Regular Joe's: Kettle Sour Pale Ale | Nantahala Brewing | | |
| Two Regular Joes | Cigar City Brewing | American Imperial Stout | 9.3% |
| Two Rivers Blanc Logsdon | Logsdon Farmhouse Ales | Saison | 8.0% |
| Two Sisters Imperial Stout | Amherst Brewing Company | American Imperial Stout | 6.7% |
| Two Stall | Ahnapee Brewing | | |
| Two Term Double IPA | Diamond Bear Brewing Co. | Imperial IPA | |
| Two Tickets to Paradise | Crooked Stave Artisan Beer Project | Saison | 4.8% |
| Two To Tangø | Night Shift Brewing | American IPA | 7.5% |
| Two Tortugas | Karl Strauss Brewing Company | Quadrupel (Quad) | 11.1% |
| Two Tugs | Half Acre Beer Company | American Brown Ale | 8.0% |
| Two Tun | Hermitage Brewing Company | Russian Imperial Stout | 9.0% |
| Two Unions | Atom Brewing | Wild Ale | |