| Stupid Quadrupid | Bell's Brewery, Inc. | Imperial IPA | 15.0% |
| Stupid sexy | Revelry Brewing Company | Wild Ale | 7.5% |
| Stupid Sexy Reserve | Little Earth Project | Flanders Red Ale | 6.0% |
| Stupid Sexy Suffolk | Little Earth Project | Flanders Red Ale | 6.5% |
| Stupid Silly Sour | Brasserie de Silly | Lambic | 5.5% |
| Stupid Stout | Coronado Brewing Company | American Imperial Stout | 10.0% |
| Sturgeon Stout | Mad Crab Restaurant and Brewery | American Stout | |
| Stüvenbräu Maibock | Egan Brewing | Bock | |
| Stüvenbräu Maibock | Gottberg Brew Pub | Bock | |
| Stygian Descent | Stone Brewing | Black IPA | 11.6% |
| Styrbjorn | Side Project / Evil Twin Brewing | Quadrupel (Quad) | 14.0% |
| Styrbjørn | Side Project | Quadrupel (Quad) | 14.0% |
| Styrian | Other Half Brewing Co. | | |
| Subatomico | Southern Star Brewing Company | New England IPA | 5.3% |
| Subglitch | Hudson Valley Brewery | | |