| Sparti parti | Big Lake Brewing | New England IPA | |
| Sparticle Physics | Equilibrium Brewery | | |
| Spatial Proximity | Spyglass Brewing Company | New England IPA | 8.0% |
| Spazz | Highland Park Brewery | | 4.0% |
| Spazzerack | Three Floyds Brewing | | 9.0% |
| Spazzin' Out In The Basement | Hoof Hearted Brewing | American Lager | 7.2% |
| Speak Kindly | Magnify Brewing | | |
| Speak of the Devil coconut coffee latte | Streetside Brewery | American Imperial Stout | 12.0% |
| Speaking Truth To Stupid | Woods Boss Brewing Company | Saison | 8.5% |
| Spearmint Tea Mead | Kuhnhenn Brewing | | 9.8% |
| Spears | De Garde Brewing | Wild Ale | 5.0% |
| Spears of Death | 18th Street Brewery | Russian Imperial Stout | 12.0% |
| The Special | The Black Abbey Brewing Company | Belgian Pale Ale | 6.2% |
| Special 6 | Brouwerij De Block | Belgian Pale Ale | 6.0% |
| Special Ale | Porterhouse Restaurant and Brewpub | American Amber / Red Ale | |