| Sophia Lambic | Brasserie Cantillon | Lambic | 6.5% |
| Sophie's Sparkling Ale | Appalachian Brewing Company | | 4.3% |
| Sophistry 06 | Lupulin Brewing | American IPA | 7.5% |
| Sophistry 5 | Lupulin Brewing | New England IPA | 7.5% |
| Sophocles | Mystery Brewing Company | | |
| Sophomore Blend | Brewlihan Mead Company | | |
| Sophomoric Saison | 18th Street Brewery | Saison | 7.2% |
| Soproni | Heineken Hungária | German Pilsner | 5.0% |
| Sorachi | Wiley Roots Brewing Co. | Saison | |
| Sorachi Ace | Brooklyn Brewery | Saison | 7.6% |
| Sorachi Ace Bitter | Brasserie Du Mont Salève | English Bitter | 2.5% |
| Sorachi Ace Ginger Saison | Microbrasserie Pit Caribou | Saison | 5.2% |
| Sorachi Ace Single Hop IPA | Mikkeller | American IPA | |
| Sorath | Magnanimous | Czech Dark Lager | 6.0% |
| Sorbet | Aslin | American IPA | 6.5% |