| South Hampton IPA | Southampton Publick House | American IPA | 6.2% |
| South of Eleven | Hoof Hearted Brewing | Imperial IPA | 10.2% |
| South of the Border Light | Brown Street Brewery | | |
| South Park Blonde | 21st Amendment Brewery Cafe | American Blonde Ale | 5.0% |
| South Plains Hoptimus Delirium #1 | South Plains Brewing Company | American Brown Ale | 7.8% |
| South Pole Elf | Platform Beer Co. | | 8.0% |
| South Sea Mountain | Funk Factory Geuzeria | Wild Ale | 5.0% |
| South Side | Chris Klein | | |
| South Street Experimentum | Equilibrium Brewery | Imperial IPA | 8.0% |
| South Street Imperium | Equilibrium Brewery | Imperial IPA | 8.0% |
| Southampton Grand Cru | Southampton Publick House | Belgian Pale Strong Ale | 9.5% |
| Southampton Imperial Russian Stout | Southampton Publick House | Russian Imperial Stout | 10.2% |
| Southampton Trappist IPA | Southampton Publick House | Belgian IPA | 7.1% |
| Southdown Breakfast Stout | Sand City Brewing Co. | American Stout | 7.5% |
| Southerly Love | Creature Comforts | Wild Ale | 6.8% |