| Spellbinder | Wren House Brewing | New England IPA | 7.0% |
| Spellbound | Wayfinder Brewery | American IPA | 7.2% |
| Spelling van het lot IX.VIII Aardbeiinteraties | 3 Fonteinen | | |
| Spelt Check | Icarus Brewing Company | | |
| Spelt Incorrectly | Põhjala | English IPA | 6.0% |
| Spelt Malt | Brouwerij De Moersleutel | American Stout | 11.0% |
| Spelung Van Het Lot XIV.ii Langste Nacht 2019 | 3 Fonteinen | Fruit Lambic | 5.5% |
| Spencer | The Ale Apothecary | | |
| Spencer Monks' Reserve Ale | Spencer Brewery | Quadrupel (Quad) | 10.2% |
| Spencer Trappist Ale | Spencer Brewery | Belgian Pale Ale | 6.5% |
| Spent: Black & Red | Afterthought Brewing Company | | |
| Spetsnaz | Grumpy Troll Restaurant and Brewery | Sweet / Milk Stout | 6.7% |
| Speyside Cacao | Dugges Ale/Stillwater Artisinal | American Imperial Stout | 14.0% |
| Spezial | Alpirsbacher Klosterbru | | 5.2% |
| Spezial | Brauereigasthof Adler | | 5.1% |