| Shipwrecker Circus | Oskar Blues Brewery | American Barleywine | 10.5% |
| Shipyard Bourbon Barrel Aged Double ESB | Shipyard Brewing Co. | | |
| Shipyard Bourbon Barrel Aged Prelude | Shipyard Brewing Co. | English Strong Ale | 9.7% |
| Shipyard Gladiator Series: Essedarius Barrel Aged Imperial Roman Ale | Shipyard Brewing Co. | American Barleywine | 10.5% |
| Shipyard Mint Chocolate Stout (Pugsley's Signature Series) | Shipyard Brewing Co. | American Imperial Stout | 9.0% |
| Shiraz | Zephyr Homebrew | | 14.0% |
| Shire Wood | Cherry Street Brewing Cooperative | English Barleywine | 10.0% |
| Shiro | Floodland Brewing | | 5.7% |
| Shiro’s Delight | Allagash Brewing Company | Wild Ale | 9.3% |
| Shirtless Dictator (Bourbon Barrel Aged) | Liquid Hero Brewery | Russian Imperial Stout | |
| Shiva IPA | Asheville Pizza and Brewing Co. | American IPA | 5.3% |
| Shiver: Thomas Hammer Coffee | Bombastic Brewing | | 10.5% |
| Shnoodlepip | The Wild Beer Co. | Wild Ale | 6.5% |
| Sho' Nuff | Against The Grain Brewery & Smokehouse | Belgian Pale Ale | 4.9% |
| Shoals Pale Ale | Smuttynose Brewing Co. | American Pale Ale | 4.7% |