| Sculpin India Pale Ale | Ballast Point Brewing Company | American IPA | 7.0% |
| Scumptious Spring Lager (Vinyl) | Magic Hat | | |
| Scuppadine | Fonta Flora | Wild Ale | 6.4% |
| The Scupper | Cape May Brewing Company | | |
| Scurry | Off Color Brewing | Altbier | 5.3% |
| Scurvy | Tyranena Brewing | American IPA | 6.5% |
| Scurvy Shyster Bastard | B. Nektar Meadery | | 12.0% |
| SCYLLA'S GRASP | Urban Legend Brewing Company | American Pale Ale | 5.2% |
| Scyndication | Pure Project | Flanders Red Ale | 8.1% |
| Scytale 385 | Great Basin Brewing Company | Russian Imperial Stout | 14.5% |
| Scytale 427 Tropico Reserve | Great Basin Brewing Company | American Imperial Stout | 11.8% |
| Scythe | The Drowned Lands | Pumpkin Beer | 5.7% |
| Scythe & Sickle | Brewery Ommegang | Bière de Garde | 5.8% |
| Scythe Rye IPA | Burial Beer Co. | American IPA | 7.5% |
| Sdre | Mea Culpa | Black IPA | |