| Second Anniversary Special Edition | Four Sons Brewing | | 13.9% |
| Second Breakfast | Night Shift Brewing | Baltic Porter | 10.8% |
| Second Breakfast | Track 7 Brewing | American Imperial Stout | |
| Second Breftist | Triptych Brewing | American Barleywine | 10.1% |
| Second Circle Anniversary Blend | Adroit Theory | | |
| The Second Coming | Right Brain Brewery | Imperial IPA | 8.0% |
| Second Date | Rock City Brewing | New England IPA | 7.5% |
| Second Fiddle | Fiddlehead Brewing | Imperial IPA | 8.2% |
| Second Hand Smoke | Midnight Sun Brewing Co. | American Stout | 8.4% |
| Second nature | Kent Falls Brewing Company | Wild Ale | 5.6% |
| Second Press | Private Press Brewing | | 14.3% |
| Second Serving | Mikkeller San Diego | Black IPA | 5.5% |
| Second Son | Mason Ale Works | American Strong Ale | 14.0% |
| Second Stone | Casa Agria Specialty Ales | | 5.2% |
| Second Street IPA | Second Street Brewery | American IPA | 6.0% |