| Sigma Brewing Company | |
| Sigtuna Brygghus | Arlandastad, Sweden |
| Siletz Roadhouse & Brewery | Siletz, Oregon |
| Silva Brewing | Paso Robles |
| Silver Branch Brewing Co. | Silver Spring, MD |
| Silver City Brewing Co. | Silverdale, Washington |
| Silver Gulch Brewing Company | Fox, Alaska |
| Silver Moon Brewing | Bend, oregon |
| Silverado Brewing | Saint Helena, California |
| Silversmith | Virgil, Canada |
| Simian Ales | Elmshorn, Germany |
| Simmerberg Brusttt und Taferne | Simmerberg, Germany |
| Simonds Farsons Cisk Plc. | Mriehel, Malta |
| Simple Roots | Burlington, Vermont |
| Sing Sing Kill Brewery | Ossining, New York |