| Spinach | Other Half Brewing Co. | Imperial IPA | 7.0% |
| Spinal Remains Pumpkin Stout | Spring House Brewing Company | Pumpkin Beer | 8.5% |
| Spinal tapper | Odd Side Ales | Imperial IPA | |
| Spinal Tapper | Right Brain Brewery | American IPA | 7.5% |
| Spine Tingler | Portland Brewing | Tripel | |
| Spinnerfall Saison | Fall River Brewery | Saison | 5.4% |
| Spinning Away W.E. Coast IPA | Imagine Nation Brewing Co. | New England IPA | 7.2% |
| Spinning Mule | Cedar Creek Brewery | American Porter | 7.1% |
| Spinning Tails | Calusa Brewing | Wild Ale | 6.5% |
| Spinning Vinyl | Central Standard Brewing | American Imperial Stout | 14.0% |
| Spiral Jetty | Epic Brewing Company | American IPA | 6.6% |
| Spiral Light | Toolbox Brewing Co. | Wild Ale | 8.1% |
| Spiral Staircase | 10 Barrel Brewing Co. | Imperial Porter | 9.7% |
| Spirals | Definitive Brewing Company | Imperial IPA | 8.2% |
| Spirit Animal | Blue Owl Brewing | | |