| Southern Sphere | TrimTab Brewery | New England IPA | 7.5% |
| Southern Stargazer | Garage Project | American IPA | 7.0% |
| Southern Sunrise | Sante Adairius Rustic Ales | | 7.6% |
| Southern Tier Harvest Ale | Southern Tier Brewing Co | Extra Special / Strong Bitter (ESB) | 5.7% |
| Southern Tier IPA | Southern Tier Brewing Co | American IPA | 6.5% |
| Southern Tier Porter | Southern Tier Brewing Co | American Porter | 5.2% |
| Southern Tier Tripel | Southern Tier Brewing Co | Tripel | 9.0% |
| Southern Triangle | Rough Draft | American IPA | 6.5% |
| Southernly Love | Creature Comforts | Wild Ale | 6.8% |
| Southhampton Pumpkin Ale | Southampton Publick House | Pumpkin Beer | 5.5% |
| Southlea | Fatty's Beer Works | | |
| Southport Amber | Brewmasters Restaurant and Brewery South | American Amber / Red Ale | |
| Southward | Casita Cerveceria | American Stout | 11.0% |
| Southy Bitch Slap | Pig Minds Brewing Co. | Irish Red Ale | 7.3% |
| Sovereign Super Saison | Four Winds Brewing | Saison | 8.5% |