| The Sister | Fremont Brewing Company | Imperial IPA | 8.5% |
| Sister, Mother, Daughter | Anchorage Brewing Co | English Barleywine | 16.0% |
| Sisterhood Sour | Lawson's Finest Liquids | Berliner Weisse | 5.0% |
| Sisu - Barrel-Aged Finnish-style Stout | Upper Hand Brewery | Russian Imperial Stout | 10.0% |
| Sisyphus | Mortalis | | |
| Sisyphus Barleywine | Real Ale Brewing Company | American Barleywine | 11.1% |
| Sit Down Son | Carton Brewing Company | | |
| Sit Tight | Magnify Brewing | | |
| Sitdown Paddleboard | Brouwerij Frontaal | English IPA | 4.7% |
| Sitopia | Antidoot - Wilde Fermenten | | |
| Sitting In Stillness | Amalgam | American Imperial Stout | 14.3% |
| Situational Awareness | Bottle Logic | American Imperial Stout | 13.0% |
| Situational Ethics (Maple Bourbon Barrrels and Cinnamon) | Monday Night Brewing | American IPA | 13.9% |
| Situational Ethics (Maple Rum Barrel) | Monday Night Brewing | American Imperial Stout | 13.8% |
| Situational Ethics (Meadowfoam Honey Apple Brandy Barrel Aged) | Monday Night Brewing | American Imperial Stout | 13.8% |