| Second Date | Rock City Brewing | New England IPA | 7.5% |
| Second Death | Holy Mountain | Helles | 4.8% |
| Second Fiddle | Fiddlehead Brewing | Imperial IPA | 8.2% |
| Second Hand Smoke | Midnight Sun Brewing Co. | American Stout | 8.4% |
| Second nature | Kent Falls Brewing Company | Wild Ale | 5.6% |
| Second Press | Private Press Brewing | | 14.3% |
| Second Serving | Mikkeller San Diego | Black IPA | 5.5% |
| Second Son | Mason Ale Works | American Strong Ale | 14.0% |
| Second Stone | Casa Agria Specialty Ales | | 5.2% |
| Second Street IPA | Second Street Brewery | American IPA | 6.0% |
| Second Sun | Arbor Brewing Company | Wild Ale | 6.8% |
| Second Wind Pale Ale | Mother Earth Brewing | American Pale Ale | 5.0% |
| Seconds: A First Anniversary Beer | Cellador Ales | Wild Ale | 6.9% |
| Secret Admirer | Alewerks Brewing Company | Imperial IPA | 8.3% |
| Secret Admirer | Williamsburg AleWerks | Imperial IPA | 8.0% |