| Last Call B.A. 2021 | Brouwerij Frontaal | Russian Imperial Stout | 10.0% |
| Last Chance IPA | Weyerbacher Brewing Company | American IPA | 5.9% |
| Last Christmas | Eagle Park Brewing | | 14.4% |
| Last Fathom | Lake Monster | Munich Dunkel | 5.5% |
| The Last Four Winters in Wisconsin | Funk Factory Geuzeria | Wild Ale | 5.5% |
| The Last Gentleman | Strange Land Brewery | English Porter | 6.8% |
| Last Hurrah | Cape May Brewing Company | | 15.0% |
| Last Kiss Wee Heavy | Pipeworks Brewing Company | Scotch Ale / Wee Heavy | 9.5% |
| Last Mayan Dog | Thirsty Dog Brewing | | 7.0% |
| Last Minute | Moor Beer Company | English Porter | 7.1% |
| Last O.G. | Mikkeller San Diego | American Imperial Stout | 14.3% |
| Last OG - Trey | Mikkeller | Russian Imperial Stout | 14.4% |
| Last Place Stout | Blue Tarp Brewing | American Imperial Stout | |
| Last Rays | Temporal Artisan Ales | | 5.8% |
| Last Request | Jailhouse Brewing Company | American Stout | 8.0% |