| Deerhunter BA 2021 VOL. I | Brouwerij Frontaal | Russian Imperial Stout | 13.4% |
| Deesko! | Three Barrel Brewing Company | Berliner Weisse | |
| Deesko! | Three Floyds Brewing | Berliner Weisse | 6.5% |
| Deetz | Bevog Brewery | | 4.8% |
| Deez Nuts | 105 West Brewing Company | English Bitter | 4.3% |
| Deez... | Prairie Artisan Ales | American Imperial Stout | 12.0% |
| Defacto 0433 | Northern Lights Brewing | Imperial IPA | 9.0% |
| deFallt | Taxman Brewing Co. | Bière de Garde | 7.0% |
| deFallt - Bourbon Barrel | Taxman Brewing Co. | Bière de Garde | 8.0% |
| Defender IPA | Brooklyn Brewery | American IPA | 6.7% |
| Defending The West | Insight Brewing | American IPA | 7.6% |
| Defenestration | Russian River Brewing Company | Belgian Pale Ale | 6.8% |
| Defiance Pale Ale | Brixton Brewery | English IPA | 4.5% |
| Definitely contains nuts | Beau's All Natural Brewing Co. | | 6.7% |
| Definitive Ale | Definitive Brewing Company | American IPA | 6.7% |