| Spacewalker American Belgo | Great Lakes Brewing | Belgian IPA | 8.2% |
| Spacious Skies | Family Business Beer Co. | American Lager | 4.0% |
| Spades | Stroom | Irish Red Ale | 5.2% |
| Spaghetti Western | Brewfist brewery | Foreign / Export Stout | 9.0% |
| Spaghetti Western | Prairie Artisan Ales / Brewfist | | |
| The Spaghetti Western Imperial Chocolate Coffee Stout Aged In Grappa Barrels | Brewfist brewery | | 10.8% |
| Spanish Sherry Barleywine | Newburgh Brewing Company | American Barleywine | 12.0% |
| Spank Me Baby! | Tyranena Brewing | American Barleywine | 9.0% |
| Spanning & Sensatie | Brouwerij De Molen | Russian Imperial Stout | 9.8% |
| Spare Time | Good City Brewing Co | American IPA | 5.4% |
| Spark In The Dark | Brouwerij Kees | American Imperial Stout | 11.5% |
| Sparkle Muffin | Revision Brewing. Company | New England IPA | 7.0% |
| Sparkleberry | Bell's Brewery, Inc. | Tripel | 9.0% |
| Sparklepuff, Galaxy Starfighter Defender of the Universe | Flying Monkeys Craft Brewery | | 10.2% |
| Sparkles Finds (Some) Trouble Hibiscus Gose | Off Color Brewing | Gose | 4.5% |