| Big Slick | Ale Asylum | American Stout | 7.0% |
| Big Slick American Barleywine Ale | Midnight Sun Brewing Co. | American Barleywine | 11.9% |
| Big Slide IPA | Lake Placid Pub & Brewery | | 7.0% |
| The Big Smoke | 8 Wired Brewing Co. | Smoked Beer | 6.2% |
| Big Snail | Jackie O's Pub & Brewery | American Imperial Stout | 13.2% |
| Big Sound Scotch Ale | Cigar City Brewing | Scottish Ale | 8.5% |
| Big Sound Scotch Ale - Bourbon | Cigar City Brewing | Scotch Ale / Wee Heavy | 8.5% |
| Big Spill Pils | Wren House Brewing | German Pilsner | 4.7% |
| Big Splash Pale | Shelter Brewing | Low Alcohol Beer | 0.0% |
| Big Sprang | Trillium | Kölsch | 7.5% |
| Big Stache | Pentrich Brewing Co. | Imperial IPA | 8.4% |
| Big Star White IPA | Four String Brewing | Belgian IPA | 7.0% |
| Big Stick | Sick-N-Twisted | American Blonde Ale | 5.7% |
| Big Sur | Barrelhouse Brewing Co. | Imperial IPA | 9.6% |
| Big Swede | Valkyrie Brewing | | 8.5% |