| Universal Mind | Resident Culture Brewing Company | New England IPA | 6.5% |
| Universal Principle | Garage Project | Saison | 7.8% |
| UniversAle Pale | Fremont Brewing Company | American Pale Ale | 5.6% |
| The Universe Is Indifferent | Tree House Brewing Company | American Imperial Stout | 10.8% |
| Unjunct | Carton | American Stout | 8.5% |
| Unjunct | Carton Brewing Company | American Stout | 8.5% |
| Unkel Brett | Microbrasserie Sutton Brouërie | European Dark Lager | 5.3% |
| Unknown | Shmaltz Brewing Company | | |
| Unknown Beast | DSSOLVR | Schwarzbier | 5.0% |
| Unknown Beginning | Old Thunder Brewing Company | Old Ale | 10.0% |
| Unknown Bottle | Westminster Brewing Company | | |
| Unknown Soldier | The Livery | Wild Ale | |
| Unleash The Yeast: American Ale | BrewDog Ltd | American Pale Ale | 6.3% |
| Unleash The Yeast: Bavarian Weizen | BrewDog Ltd | Hefeweizen | 6.3% |
| Unleash The Yeast: Belgian Trappist | BrewDog Ltd | Belgian Pale Ale | 6.3% |