| Two Hundred Fathoms 2022 | Galway Bay Brewery | Russian Imperial Stout | 10.8% |
| Two James 4th. D old ale | Kuhnhenn Brewing | Old Ale | 13.5% |
| Two Jokers Double-Wit | Boulder Beer Company | Witbier | 8.0% |
| Two Jokers Double-Wit | Boulevard Brewing Company | Witbier | 8.0% |
| Two juicy | Two Roads Brewing Co. | American IPA | 8.2% |
| Two Levees - Raspberry Tart | Urban South Brewery | Wild Ale | |
| Two Lights | Allagash Brewing Company | Bière de Champagne / Bière Brut | 6.7% |
| Two Lions Pale Ale | Taylor's Crossing Brewing | American Pale Ale | |
| Two Penny Porter | Birrificio Ticinese | American Porter | 8.2% |
| Two Pilots | Sante Adairius Rustic Ales | Saison | 7.0% |
| Two Princes | Streetside Brewery | Fruit and Field Beer | 4.5% |
| Two Regular Joe's: Kettle Sour Pale Ale | Nantahala Brewing | | |
| Two Regular Joes | Cigar City Brewing | American Imperial Stout | 9.3% |
| Two Rivers Blanc Logsdon | Logsdon Farmhouse Ales | Saison | 8.0% |
| Two Sisters Imperial Stout | Amherst Brewing Company | American Imperial Stout | 6.7% |