| Up The Bourbon Barrel Quad | Listermann Brewing Company | Quadrupel (Quad) | 10.5% |
| Up The Creek | Thomas Creek Brewery | | |
| Up Up Down Down | Tombstone Brewing Company | New England IPA | 7.6% |
| Up Up Down Down Left Right Left Right BA | Narrow Gauge Brewing Company | Imperial IPA | 8.1% |
| Up, Up & Away | 2SP Brewing Company | New England IPA | 8.0% |
| Up, Up, & Away | Magnify Brewing | | |
| Upheaval IPA | Widmer Brothers Brewing | | |
| Upland Wheat Ale | Upland Brewing | American Pale Wheat Beer | 4.5% |
| Upon the Shattered Cliffs | Bolero Snort | American Porter | 10.7% |
| Upon the Shattered Cliffs w/ Hazelnuts, Maple Syrup & Cinnamon | Czig Meister | | |
| Upper Case | Trillium Brewing Company | Imperial IPA | 9.0% |
| Upper Middle Class Oblivion | Nøgne Ø | | 12.0% |
| Upper Peninsula Ale (UPA) | Upper Hand Brewery | American Pale Ale | 5.5% |
| Uppers Downers All Arounders | Prairie Artisan Ales | American Imperial Stout | 14.0% |
| Upright Untitled (Bad Brains) | Upright Brewing Company | | |