| Syndicate No. 1 | Speakeasy Ales and Lagers | American Strong Ale | 10.5% |
| Syndicate No. 2 | Speakeasy Ales and Lagers | | 10.5% |
| Syndicate No. 3 | Speakeasy Ales and Lagers | American Strong Ale | 10.5% |
| Synopsis - Black Currant | Area Two | Wild Ale | 6.4% |
| Synopsis - Prickly Pear | Area Two | Wild Ale | 6.4% |
| Synth Wave | Alefarm Brewing | Imperial IPA | 7.4% |
| Synthesis | Oxbow Brewing Company | Saison | 8.0% |
| Synthesis Analogous | Jester King Craft Brewery | Wild Ale | 5.6% |
| Synthesis Vanilla Chai | Brewlihan Mead Company | | |
| Syracuse Pale Ale | Middle Ages Brewing | American Pale Ale | 5.0% |
| Syrah | Fair Isle Brewing | Fruit and Field Beer | 8.9% |
| Syrah Smile | The Bruery | | |
| Syrah Tilquin à l'Ancienne | Gueuzerie Tilquin | Fruit Lambic | 8.0% |
| Syrah Tilquin à l'Ancienne (2021-2022) | Gueuzerie Tilquin | | 8.0% |
| Syrligt | Dugges Ale/Stillwater Artisinal | Fruit and Field Beer | 4.5% |