| Spiritus Mundi - Coffee & Coconut | Incendiary Brewing Company | American Imperial Stout | 13.0% |
| Spiteful IPA | Spiteful Brewing Company | American IPA | 6.2% |
| Spitfire | Santiam Brewing Company | Extra Special / Strong Bitter (ESB) | 6.2% |
| Spitfire Best Bitter | Flyers Restraunt and Brewery | English Bitter | 4.0% |
| Spitfire Premium Kentish Strong Ale | Shepherd Neame | | 4.5% |
| Spittin' Seeds | The Buzz Meadery | | 6.6% |
| Splash | 2 Fools Cider | Fruit and Field Beer | 4.0% |
| The splash | Brussels Beer Project | New England IPA | 6.0% |
| Splash: White | Funky Fluid | Gose | 3.6% |
| Splashdown at Sunrise | Bottle Logic | Fruit and Field Beer | 6.5% |
| Splendid Population | Almanac Beer Co. | Wild Ale | 8.8% |
| Splendid Squishy | Oliphant | Fruit and Field Beer | 5.6% |
| Splice the Mainbrace | Ghost Train Brewing | American Strong Ale | 10.5% |
| Splinter Black | Troegs Brewing | American Imperial Stout | 11.0% |
| Splinters | Black Raven Brewing Co. | | |