| Sliced Can | Wicklow wolf | American Lager | 3.0% |
| Sliced Mango | HOMES Brewery | Wild Ale | 6.5% |
| Slick Nick Winter Ale | Sebago | | |
| Slide Down My Cellar Door | Cellador Ales | Wild Ale | 6.5% |
| Sliderule | Urban Artifact | | 4.9% |
| Sliding Into The DMs | Evil Genius Beer Company | Cream Ale | 6.0% |
| Slightly Mighty | Dogfish Head Craft Brewery | American IPA | |
| Sligo Red | O'Gara's Bar & Grill | | |
| Slim Digs West Coast IPA | Gold Dot Beer | American IPA | 7.4% |
| Slings & Arrows | Indie Ale House Brewing Company | Berliner Weisse | 4.2% |
| SlingShot | Backpocket Brewing | Dunkelweizen | |
| Slipknot IPA | Full Sail Brewing | English IPA | 7.0% |
| Slippery Detour (Vanilla) | Detour Brewing | Cream Ale | 5.1% |
| Slippery Slope | Brouwerij De Moersleutel | Oatmeal Stout | 12.0% |
| Slippin' Into Darkness | Franklin's Restaurant, Brewery & General Store | Wild Ale | 9.0% |