| Shelby Blue Ribbon | New Day | | |
| Shell Game | Kane Brewing Company | American Imperial Stout | 13.8% |
| Shelled | Sapwood Cellars | American Imperial Stout | 11.8% |
| Shells | Wunderkammer Bier | Wild Ale | 4.5% |
| Shelter Pale Ale | Dogfish Head Craft Brewery | American Pale Ale | 5.0% |
| Shelton | Oshlag | Saison | 6.5% |
| Shenanigans | Odell Brewing | Wild Ale | 9.1% |
| Shenanigans Summer Ale | Indeed Brewing Company | American Pale Wheat Beer | 4.6% |
| Shepard's Crook Scotish Ale | Rivertowne Pour House | Scottish Ale | 5.1% |
| Shepherd's Delight | Baa Baa Brewhouse | New England IPA | 6.9% |
| Sherbrooke Chocolate Cherry Ostiarius | Alley Kat Brewing Company | American Porter | 6.5% |
| Sheridan | Night Shift Brewing | Flanders Red Ale | 9.2% |
| Sheriff Dobeck | Kinship Brewing Company | Russian Imperial Stout | 10.0% |
| Sherman Bock | 903 Brewers | Bock | 7.1% |
| Sherpa's Survival Kit SC Edition | Forager Brewery | American Imperial Stout | 10.6% |