| Sirius | Lagunitas Brewing Company | Cream Ale | 7.0% |
| Sirius Black | The Rare Barrel | Wild Ale | 6.4% |
| Sirkawa - Costa Rica - Cognac | Brasserie Dunham | Russian Imperial Stout | 9.5% |
| Sirkawa - Costa Rica - Porto | Brasserie Dunham | Russian Imperial Stout | 9.5% |
| Sirkawa Colombie | Brasserie Dunham | Russian Imperial Stout | 9.5% |
| Sirkawa Costa Rica | Brasserie Dunham | Russian Imperial Stout | 9.5% |
| Sirkawa El Salvador | Brasserie Dunham | Russian Imperial Stout | 9.5% |
| Sirkawa Guatemala | Brasserie Dunham | Russian Imperial Stout | 10.0% |
| The Sister | Fremont Brewing Company | Imperial IPA | 8.5% |
| Sister, Mother, Daughter | Anchorage Brewing Co | English Barleywine | 16.0% |
| Sisterhood Sour | Lawson's Finest Liquids | Berliner Weisse | 5.0% |
| Sisu - Barrel-Aged Finnish-style Stout | Upper Hand Brewery | Russian Imperial Stout | 10.0% |
| Sisyphus | Mortalis | | |
| Sisyphus Barleywine | Real Ale Brewing Company | American Barleywine | 11.1% |
| Sit Down Son | Carton Brewing Company | | |