| Secret Space of Dreams | Pure Project | Russian Imperial Stout | 16.5% |
| Secret Spot | Green Room Brewing | American Imperial Stout | |
| Secret Spot - 2013 Anniversary Ale | Green Room Brewing | American Imperial Stout | 10.0% |
| Secret Spot 2016 | Green Room Brewing | American Imperial Stout | 11.0% |
| Secret Spot- 2015 | Green Room Brewing | Russian Imperial Stout | 10.0% |
| Secret Stache Stout | Finch's Beer Co. | | 5.3% |
| Secret Stairs | Trillium | American Stout | 6.5% |
| Secret Stairs | Trillium Brewing Company | American Stout | 6.5% |
| The Secret Truth of the Universe | Barebottle Brewing Company | American IPA | 6.6% |
| Sede Vacante | The Lost Abbey | American Strong Ale | 15.0% |
| Sedici Gradi | Birra Del Borgo | English Barleywine | |
| Sedicigradi | Birra Del Borgo | English Barleywine | 16.0% |
| Seditious Ways | The Rare Barrel | Wild Ale | 6.9% |
| Sedlec 12° | Human Robot Brewing | Bohemian / Czech Pilsner | 5.4% |
| Seduction | Brewery Ommegang | Belgian Dark Ale | 6.8% |