| Secession Black India Pale Ale (CDA) | Hopworks Urban Brewery | | 6.5% |
| Secessionist #1 (Gingerbread Stout) | Buffalo Bayou | American Imperial Stout | 10.0% |
| Second | Barrel Theory | American Imperial Stout | 12.0% |
| Second Anniversary - Grand Cru | Figueroa Mountain Brewing Co. | Belgian Dark Strong Ale | 10.7% |
| Second Anniversary Ale | Hardywood Park Craft Brewery | Tripel | 10.5% |
| Second Anniversary Ale | Three Magnets Brewery | | |
| Second Anniversary Special Edition | Four Sons Brewing | | 13.9% |
| Second Breakfast | Night Shift Brewing | Baltic Porter | 10.8% |
| Second Breakfast | Track 7 Brewing | American Imperial Stout | |
| Second Breftist | Triptych Brewing | American Barleywine | 10.1% |
| Second Circle Anniversary Blend | Adroit Theory | | |
| The Second Coming | Right Brain Brewery | Imperial IPA | 8.0% |
| Second Date | Rock City Brewing | New England IPA | 7.5% |
| Second Fiddle | Fiddlehead Brewing | Imperial IPA | 8.2% |
| Second Hand Smoke | Midnight Sun Brewing Co. | American Stout | 8.4% |