| One Lion | Lickinghole Creek Craft Brewery | Sweet / Milk Stout | 8.5% |
| One Man Band | Bearded Iris Brewing | American Barleywine | 10.0% |
| One Man Mosh Pit | Surly Brewing Co. | New England IPA | 7.2% |
| One Man Wrecking Machine | Mikerphone | American Imperial Stout | 11.5% |
| One Million Eight Hundred And Seventy Thousand Million | Transient Artisan Ales | | |
| One Million Tomorrows | Modern Times | | |
| One Million Tomorrows with Nectarines | Modern Times | Saison | 7.7% |
| One More Again | Hoof Hearted Brewing | Bohemian / Czech Pilsner | 4.5% |
| One More Line | SquareHead Brewing Company | Dunkelweizen | 6.8% |
| One more robot | Homage Brewing | | |
| One More Time | New Image Brewery | New England IPA | 7.8% |
| One Nut Brown Ale | Oskar Blues Brewery | American Brown Ale | 5.0% |
| One Oatmeal Stout | Dark Horse Brewing Co. | Oatmeal Stout | |
| One of the Classic blunders | Triptych Brewing | Imperial IPA | 8.8% |
| One Off [BANISHED] Wild Golden Sour Ale | Crux Fermentation Project | Wild Ale | 10.0% |