| The Last And Final Judgement | Mystic Brewery | Quadrupel (Quad) | 11.0% |
| Last Apple | Moonlight Meadery | | 16.0% |
| The Last Blockbuster | 10 Barrel Brewing Co. | Black IPA | 5.7% |
| Last Brunch | Forgotten Boardwalk | | 6.7% |
| Last Buffalo In the Park | Funky Buddha Lounge and Brewery | American Porter | 11.5% |
| Last Buffalo in the Park Louisville White Wax - The Living Barrel Series | Funky Buddha Lounge and Brewery | American Porter | 11.5% |
| Last Call B.A. 2021 | Brouwerij Frontaal | Russian Imperial Stout | 10.0% |
| Last Chance IPA | Weyerbacher Brewing Company | American IPA | 5.9% |
| Last Christmas | Eagle Park Brewing | | 14.4% |
| Last Fathom | Lake Monster | Munich Dunkel | 5.5% |
| The Last Four Winters in Wisconsin | Funk Factory Geuzeria | Wild Ale | 5.5% |
| The Last Gentleman | Strange Land Brewery | English Porter | 6.8% |
| Last Hurrah | Cape May Brewing Company | | 15.0% |
| Last Kiss Wee Heavy | Pipeworks Brewing Company | Scotch Ale / Wee Heavy | 9.5% |
| Last Mayan Dog | Thirsty Dog Brewing | | 7.0% |