| Isle Of MaGourdo | Due South | | |
| Isle of Tortuga | Heist Brewery | | |
| ISO-Hazy | Figleaf Brewing Company | American IPA | 7.2% |
| ISO: Chuck Biscuits FT: Citra | Hoof Hearted Brewing | Gose | 4.5% |
| ISO: Chuck Biscuits FT: Simcoe | Hoof Hearted Brewing | Gose | 4.5% |
| ISO: Tacos | American Solera | Russian Imperial Stout | 13.0% |
| Isola-tion | Horus Aged Ales | | |
| Isolation - Mosaic | Roses by the Stairs Brewing Company | American IPA | 6.5% |
| Isolation Ale | Odell Brewing | Winter Warmer | 6.0% |
| Isostatic Rebound | Elder Pine Brewing & Blending | German Pilsner | 5.4% |
| Issaquah Bullfrog Ale | Rogue Ales | American Pale Wheat Beer | |
| Isseki Nicho | Brasserie Dieu du Ciel | Saison | 9.5% |
| Isseki Nicho (fut de pinot noir) | Brasserie Dieu du Ciel | | |
| Istället För... | Emmaboda Bryggeri | Belgian Dark Strong Ale | 9.0% |
| iStout | 8 Wired Brewing Co. | Russian Imperial Stout | 10.0% |