| Upper Peninsula Ale (UPA) | Upper Hand Brewery | American Pale Ale | 5.5% |
| Uppers Downers All Arounders | Prairie Artisan Ales | American Imperial Stout | 14.0% |
| Upright Untitled (Bad Brains) | Upright Brewing Company | | |
| Uprising | Iron Fist Brewing Company | Belgian IPA | 12.0% |
| Uprising Barrel Aged Stout | Sons of Liberty Beer & Spirits Co | | |
| Uprising Beechwood Smoked Bourbon Barrel Aged Stout | Sons of Liberty Beer & Spirits Co | | |
| Uprising Bourbon Barrel Aged Stout | Sons of Liberty Beer & Spirits Co | | |
| Uprising Peat Smoked Bourbon Barrel Aged Stout | Sons of Liberty Beer & Spirits Co | | |
| Uprising Pedro Ximenez Sherry Barrel Aged Stout | Sons of Liberty Beer & Spirits Co | | |
| UpRiver Lager | Mudshark Brewing | Light Lager | |
| Uprooted | Side Project | Saison | 6.5% |
| UPSIDE | HOMES Brewery | | 6.8% |
| Upside Brown | Brewery Ommegang | Bière de Garde | 7.0% |
| The Upside Down | Bottle Logic | Fruit and Field Beer | 5.3% |
| Upside Down | True Brew | | 4.2% |