| The Serine | De Garde Brewing | | |
| The Serinier | De Garde Brewing | Wild Ale | 8.5% |
| Serious Leisure | Jessup Farm Barrel House | New England IPA | 8.5% |
| Seriously Bad Elf | Ridgeway Brewing | | 9.0% |
| Seriously Low Budget Cucumber Berliner Weisse | Flat Tail Brewing | Berliner Weisse | 4.0% |
| Serpent | Brooklyn Brewery | Belgian Pale Strong Ale | 9.5% |
| Serpent | Thornbridge | | 9.5% |
| Serpent and the Worm | Wild Horse | Saison | |
| Serpent's Stout | The Lost Abbey | American Imperial Stout | 10.5% |
| Serpent's Stout - Blended Bourbon Barrel-Aged | The Lost Abbey | American Imperial Stout | 11.0% |
| Serpent's Stout - Bourbon Barrel Aged | The Lost Abbey | American Imperial Stout | 13.7% |
| Serpents Stout | Lost Abbey/ Brasserie Dupont | American Imperial Stout | 11.0% |
| Serrano Pepper Ale | Saugatuck Brewing Company | | 6.8% |
| Serrata | Jester King Craft Brewery | Saison | 5.6% |
| Serum | DuClaw | Imperial IPA | 9.0% |